(ah-see-tick ass-id) Vinegar
GI ACIDIFIER
Acetic acid is used via its acidifying qualities in ruminants to treat non-protein nitrogen-induced (e.g., urea poisoning) ammonia toxicosis. It is also used as a potential treatment to prevent enterolith formation in horses by reducing colonic pH.
Acetic acid in the rumen lowers pH due to shifting ammonia to ammonium ions and reducing absorption. It may also slow the hydrolysis of urea.
No information was noted.
Should not be administered to ruminants until potential lactic acidosis (grain overload, rumen acidosis) is ruled out.
Because of the unpleasant taste and potential for causing mucous membrane irritation, acetic acid is generally recommended for administration via stomach tube.
When used for appropriate indications there is little likelihood of serious toxicity occurring after minor overdoses. Due to its potential corrosiveness, the greatest concern would occur if a concentrated form of acetic acid was mistakenly used. However, one human patient who had glacial acetic acid used instead of 5% acetic acid during colposcopy (cervix) demonstrated no detectable harm.
There are no documented drug interactions with oral acetic acid, but because of its acidic qualities it could, potentially, affect the degradation of several drugs in the gut.
For cattle with putrefaction of rumen associated with a high rumen pH:
a) 4–10 liters of vinegar (Constable 1993)
For treatment of urea poisoning:
a) Using 5% acetic acid (vinegar) infuse 2–6 liters (for cattle) into rumen; may be repeated as necessary if clinical signs reoccur. Recovery ranges from 8–24 hours. A post-recovery pro-biotic rumen inoculation may enhance the gain and productivity of urea poisoned animals. (Hall 2006)
For enterolith prevention: a) Using vinegar: 250 mL/450 kg body weight PO once daily (Robinson 1992)
Glacial acetic acid is C2H4O2. Acetic acid has a distinctive odor and a sharp acid taste. It is miscible with water, alcohol or glycerin. Much confusion can occur with the percentages of C2H4O2 contained in various acetic acid solutions. Acetic Acid USP is defined as having a concentration of 36–37% C2H4O2. Diluted Acetic Acid NF contains 5.7–6.3% w/v of C2H4O2. Solutions containing approximately 3–5% w/v of C2H4O2 are commonly known as vinegar. Be certain of the concentration of the product you are using and your dilutions.
Acetic acid may also be known as: E260, eisessig (glacial acetic acid), essigsaure, etanoico, or ethanoic acid.
Acetic acid solutions should be stored in airtight containers.
If diluting more concentrated forms of acetic acid to concentrations equivalent to vinegar (3-5%), use safety precautions to protect eyes and skin. It is strongly recommended to have someone check your calculations to prevent potentially serious consequences.
VETERINARY-LABELED PRODUCTS: None
HUMAN-LABELED PRODUCTS: None
There are no systemic products commercially available. Acetic acid (in various concentrations) may be purchased from chemical supply houses. Distilled white vinegar is available in gallon sizes from grocery stores.